Differential Protein Abundance Results

Published

Jun 2026

Differential protein abundance analysis identifies proteins that differ between biological conditions.

Basic Result Interpretation

positive log2FC  → higher in numerator condition
negative log2FC  → lower in numerator condition
small padj       → stronger statistical evidence

Significant Differentially Abundant Proteins

A common starting threshold is:

padj < 0.05

Optional effect-size filtering may include:

abs(log2FC) >= 1

# Differential Protein Abundance Results

Differential protein abundance analysis identifies proteins that differ between biological conditions.

## Basic Result Interpretation

```text
positive log2FC  → higher in numerator condition
negative log2FC  → lower in numerator condition
small padj       → stronger statistical evidence
```

## Significant Differentially Abundant Proteins

A common starting threshold is:

```text
padj < 0.05
```

Optional effect-size filtering may include:

```text
abs(log2FC) >= 1
```